INDICATIONS AND USAGE（适应症）

QINLOCK is indicated for the treatment of adult patients with advanced gastrointestinal stromal tumor (GIST) who have received prior treatment with 3 or more kinase inhibitors, including imatinib.

DOSAGE（服用剂量）

The recommended dosage of QINLOCK is 150 mg orally once daily with or without food until disease progression or unacceptable toxicity.

Instruct patients to swallow tablets whole.

Advise patients to take QINLOCK at the same time each day.

Advise patients to take a missed dose if less than 8 hours have passed since the missed scheduled dose.

Advise patients not to take an additional dose if vomiting occurs after taking QINLOCK and to continue with their next scheduled dose.

ADVERSE REACTIONS（不良反应）

Palmar-Plantar Erythrodysesthesia Syndrome

New Primary Cutaneous Malignancies

Hypertension

Cardiac Dysfunction

For full information, please refer to:

https://nctr-crs.fda.gov/fdalabel/services/spl/set-ids/9f18e462-03dd-4296-a02a-a0577e3ee78d/spl-doc?hl=Ripretinib

Qinlockinformation