All Names： Pirfenidone，pirfenex，Etuary
Indications：idiopathic pulmonary fibrosis (IPF)
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INDICATIONS AND USAGE
Pirfenidone is indicated for the treatment of idiopathic pulmonary fibrosis (IPF).
The recommended daily maintenance dosage of ESBRIET is 801 mg three times daily for a total of 2403 mg/day. Doses should be taken with food at the same time each day.
Upon initiation of treatment, titrate to the full dosage of 2403 mg/day over a 14-day period as follows:
Days 1 through 7: 267 mg three times daily (801 mg/day)
Days 8 through 14: 534 mg three times daily (1602 mg/day)
Days 15 onward: 801 mg three times daily (2403 mg/day)
Liver Enzyme Elevations and Drug-Induced Liver Injury
Photosensitivity Reaction or Rash
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