All Names： Twinaqt
Indications：human immunodeficiency virus type 1 (HIV-1) infection
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INDICATIONS AND USAGE
Twinaqt is indicated as a complete regimen for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in adults with no antiretroviral treatment history or to replace the current antiretroviral regimen in those who are virologically suppressed (HIV-1 RNA less than 50 copies per mL) on a stable antiretroviral regimen with no history of treatment failure and no known substitutions associated with resistance to the individual components of Twinaqt.
Twinaqt is a fixed-dose combination product containing 50 mg of dolutegravir and 300 mg of lamivudine. The recommended dosage regimen of Twinaqt in adults is one tablet taken orally once daily with or without food.
Patients co-infected with HIV-1 and HBV
Lactic acidosis and severe hepatomegaly with steatosis
Immune reconstitution syndrome
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