INDICATIONS AND USAGE（适应症）

RYBELSUS is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

DOSAGE（服用剂量）

•Start RYBELSUS with 3 mg once daily for 30 days. The 3 mg dose is intended for treatment initiation and is not effective for glycemic control.

•After 30 days on the 3 mg dose, increase the dose to 7 mg once daily.

•Dose may be increased to 14 mg once daily if additional glycemic control is needed after at least 30 days on the 7 mg dose.

•Taking two 7 mg RYBELSUS tablets to achieve a 14 mg dose is not recommended.

•If a dose is missed, the missed dose should be skipped, and the next dose should be taken the following day.

ADVERSE REACTIONS（不良反应）

•Risk of Thyroid C-cell Tumors

•Pancreatitis

•Diabetic Retinopathy Complications

•Hypoglycemia with Concomitant Use of Insulin Secretagogues or Insulin

•Acute Kidney Injury

•Hypersensitivity

For full information, please refer to:

https://nctr-crs.fda.gov/fdalabel/services/spl/set-ids/27f15fac-7d98-4114-a2ec-92494a91da98/spl-doc?hl=Rybelsus

Rybelsusinformation