INDICATIONS AND USAGE（适应症）

Pramipexole dihydrochloride tablets are indicated for the treatment of the signs and symptoms of idiopathic Parkinson's disease.

DOSAGE（服用剂量）

Pramipexole dihydrochloride tablets are taken orally, with or without food.

If a significant interruption in therapy with pramipexole dihydrochloride tablets has occurred, re-titration of therapy may be warranted.

Doses should be increased gradually from a starting dose of 0.375 mg/day given in three divided doses and should not be increased more frequently than every 5 to 7 days.

Pramipexole dihydrochloride tablets were effective and well tolerated over a dosage range of 1.5 to 4.5 mg/day administered in equally divided doses three times per day with or without concomitant levodopa (approximately 800 mg/day).

ADVERSE REACTIONS（不良反应）

Falling Asleep During Activities of Daily Living

Symptomatic Orthostatic Hypotension

Impulse Control/Compulsive Behaviors

Hallucinations

Dyskinesia

Renal Impairment

Rhabdomyolysis

Retinal Pathology

Events Reported with Dopaminergic Therapy

For full information, please refer to:

https://nctr-crs.fda.gov/fdalabel/services/spl/set-ids/a7405a56-de1c-4875-b57f-210c991474ba/spl-doc?hl=Pramipexole

Pramipexoleinformation