INDICATIONS AND USAGE

Nebivolol tablets are indicated for the treatment of hypertension, to lower blood pressure. Nebivolol tablets may be used alone or in combination with other antihypertensive agents.

DOSAGE

Hypertension

The dose of nebivolol must be individualized to the needs of the patient. For most patients, the recommended starting dose is 5 mg once daily, with or without food, as monotherapy or in combination with other agents. For patients requiring further reduction in blood pressure, the dose can be increased at 2-week intervals up to 40 mg. A more frequent dosing regimen is unlikely to be beneficial.

Renal Impairment

In patients with severe renal impairment (ClCr less than 30 mL/min) the recommended initial dose is 2.5 mg once daily; titrate up slowly if needed. Nebivolol has not been studied in patients receiving dialysis.

Hepatic Impairment

In patients with moderate hepatic impairment, the recommended initial dose is 2.5 mg once daily; titrate up slowly if needed. Nebivolol has not been studied in patients with severe hepatic impairment and therefore it is not recommended in that population.

ADVERSE REACTIONS

Low blood pressure and feeling dizzy. If you feel dizzy, sit or lie down and tell your doctor right away.

Tiredness

Slow heartbeat

Headache

Leg swelling due to fluid retention (edema). Tell your doctor if you gain weight or have trouble breathing while taking Nebivolol Tablets.

For full information, please refer to:

https://nctr-crs.fda.gov/fdalabel/services/spl/set-ids/c9d8edb5-5312-ad38-e053-2995a90a7154/spl-doc?hl=Nebivolol

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