INDICATIONS AND USAGE（适应症）

NUEDEXTA is indicated for the treatment of pseudobulbar affect (PBA).

PBA occurs secondary to a variety of otherwise unrelated neurologic conditions, and is characterized by involuntary, sudden, and frequent episodes of laughing and/or crying. PBA episodes typically occur out of proportion or incongruent to the underlying emotional state. PBA is a specific condition, distinct from other types of emotional lability that may occur in patients with neurological disease or injury.

DOSAGE（服用剂量）

The recommended starting dose of NUEDEXTA is one capsule daily by mouth for the initial seven days of therapy. On the eighth day of therapy and thereafter, the daily dose should be a total of two capsules a day, given as one capsule every 12 hours.

The need for continued treatment should be reassessed periodically, as spontaneous improvement of PBA occurs in some patients.

ADVERSE REACTIONS（不良反应）

Diarrhea Dizziness

Cough

Vomiting

Asthenia

Peripheral edema

Urinary tract infection

Influenza

Increased gamma-

Glutamyltransferase

Flatulence

For full information, please refer to:

https://nctr-crs.fda.gov/fdalabel/services/spl/set-ids/484e0918-3442-49dc-8ccf-177f1f3ee9f3/spl-doc?hl=Nuedexta

Nuedextainformation