All Names： Sirturo，Bedaquilin
Indications：pulmonary multi-drug resistant tuberculosis (MDR-TB)
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INDICATIONS AND USAGE（适应症）
SIRTURO is a diarylquinoline antimycobacterial drug indicated as part of combination therapy in the treatment of adult and pediatric patients (5 years and older and weighing at least 15 kg) with pulmonary multi-drug resistant tuberculosis (MDR-TB). Reserve SIRTURO for use when an effective treatment regimen cannot otherwise be provided.
Week 1 and Week 2:
Take your prescribed dose 1 time each day.
Week 3 to Week 24:
Take your prescribed dose 3 times a week.
Take SIRTURO doses at least 48 hours apart. For example, you may take SIRTURO on Monday, Wednesday and Friday every week from week 3 to week 24.
Do not skip SIRTURO doses. If you skip doses, or do not complete the total 24 weeks of SIRTURO, your treatment may not work as well, and your TB may be harder to treat.
If you take more SIRTURO than you should, talk to a healthcare provider right away.
The most common side effects of SIRTURO in adults include nausea, joint pain, headache, coughing up blood, or chest pain.
The most common side effects of SIRTURO in children 12 years to less than 18 years of age include joint pain, nausea and stomach pain.
The most common side effect in children 5 years to less than 12 years of age is increased level of liver enzymes in the blood.
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